Creatine and Caffeine

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posted by Enickma

I didn't realize there have been studies that show an inhibitory effect on creatine by caffeine.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=8929583&dopt=Abstract

From http://www.bodybuilding.com/fun/anssi1.htm

Caffeine is the most commonly consumed drug in the world, and athletes frequently use it as an ergogenic aid. It improves performance and endurance during prolonged, exhaustive exercise. To a lesser degree it also enhances short-term, high-intensity athletic performance.11 It is relatively safe and has no known negative performance effects, nor does it cause significant dehydration or electrolyte imbalance during exercise.11

Dr. Vandenberghe and coworkers compared the effects of creatine supplementation with creatine supplementation in combination with caffeine on muscle phosphocreatine level and performance in healthy male volunteers.12 Creatine and creatine + caffeine increased muscle phosphocreatine concentration by 4-6%. Dynamic torque production, however, was increased by 10-23% by creatine but was not changed by creatine + caffeine. Authors concluded that creatine supplementation elevates muscle phosphocreatine concentration and markedly improves performance during intense intermittent exercise. This ergogenic effect, however, was completely eliminated by caffeine intake. Additional research is needed to confirm these preliminary findings.

From "Forbidden Stacks" talking about the same study:

http://www.bodybuilding.com/fun/johnforb.htm

I will talk about Creatine again, but this time with Caffeine. DO NOT take Creatine and Caffeine at the same time. A team of Belgian researchers investigated the effect of taking creatine supplements with caffeine. The researchers recruited nine men who did regular recreational exercise, but were not at a high level of training. Each man then undertook a series of three regimes, allocated in a random order, with a three-week break in between. At no stage did the men know whether they were taking caffeine, creatine or placebo.

The timetables were as follows:

A: Creatine loading for six days, taking 0.5g of creatine monohydrate per kg of body weight per day
B: Placebo pills for 6 days
C: Creatine loading as in A, plus taking a dose of caffeine at breakfast in the last 3 days of loading. Caffeine dose was 5mg caffeine per kg of body weight (for a 70kg man, the equivalent of 3 strong cups of ground coffee, or 7 cups of tea).

Muscle creatine phosphate levels were measured before and after each regime. In addition, a series of tests to analyse muscular force were carried out on the subjects by making measurements during a standardized sequence of knee extension exercises. When creatine supplements were given, knee muscle force was boosted significantly, as would be expected given the raised muscle levels of creatine phosphate. But, guess what happened! Although caffeine-plus-creatine raised muscle phosphocreatine levels above placebo, the boost to muscle performance seen with creatine alone was completely missing! Reference: "Caffeine counteracts the ergogenic action of muscle creatine loading", Vandenberghe et al, J Appl Physiol, vol 80, pp452-457, 1996.

Solution: It is better if you weight train after your breakfast, forgeting coffee at that time. If you train at the afternoon, avoid drinking coffee before you leave from your work. Try to have at least 4-5 hours difference between your coffee and your Creatine serving for better results. (Caffeine stays in your system longer than most other stimulants. Half the caffeine you drink in a cup of coffee may still be coursing through your veins four hours later). So for any one of you that is taking a loading phase of Creatine, forget coffee for 4-5 days.

posted by cosmic-dust

good read, thanks

posted by Enickma

I thought it was interesting. If this is true, it would mean that the creatine in No-Xplod provides little to no benefit where the rubber meets the road. You'd might as well be popping Vivarin...lol.

posted by Dex

thats why they have you do the whole stack, noxplode, cellmass, and nitrix. you get a little of it but i use the pre workout stuff for the boost not the creatine.

good read though.

posted by cosmic-dust

I was just thinking of this and wondered if there is any effect guarana has on creatine in the same manner?

posted by Enickma

I'd bet it does actually

http://en.wikipedia.org/wiki/Caffeine

Caffeine is a xanthine alkaloid compound that acts as a stimulant in humans. Caffeine is sometimes called guaranine when found in guarana

posted by son_of_jorel135

Enickma is the C verus C effect your talking about just during the loading phase

posted by son_of_jorel135

???????

posted by yancy

can i chew cresatine pills instead of swallowing them

posted by csyflt

wow, good post my man. that will make you think.

posted by jasonlaw

read the rules moron... if your here for one reason then leave

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